CEAD-146鏄�涓�閮ㄧ敱鏃ユ湰钁楀悕鎴愪汉褰辩墖鍒朵綔鍏�鍙稿彂琛岀殑鎴愪汉褰辩墖锛屼綔涓鸿�ョ郴鍒楃殑涓�閮ㄥ垎锛屽畠浜庢煇涓�鐗瑰畾鐨勬椂闂村彂甯冦�傝櫧鐒跺叧浜庤繖閮ㄥ奖鐗囩殑鍏蜂綋鎯呰妭銆佹紨鍛樺拰鑳屾櫙鐨勪俊鎭�鏈夐檺锛屼絾鎴戜滑鍙�浠ュ洿缁曟棩鏈�鎴愪汉褰辫�嗕骇涓氱殑鐗圭偣銆佸競鍦鸿秼鍔夸互鍙婄ぞ浼氭枃鍖栬儗鏅�杩涜�屾繁鍏ユ帰璁ㄣ��
### 涓�銆佹棩鏈�鎴愪汉褰辫�嗕骇涓氭�傝堪
鏃ユ湰鐨勬垚浜哄奖瑙嗕骇涓氭湁鐫�鎮犱箙鐨勫巻鍙诧紝鏃╁湪20涓栫邯鍒濓紝鑹叉儏褰辩墖灏卞湪鏃ユ湰鐨勯粦甯備腑鎮勭劧娴佽�屻�傞殢鐫�鏃堕棿鐨勬帹绉伙紝鏀垮簻瀵规垚浜哄唴瀹圭殑鐩戠�￠�愭笎鏀炬澗锛屾垚浜哄奖鐗囬�愭笎璧板叆澶т紬瑙嗛噹銆傚湪1980骞翠唬锛岄殢鐫�褰曞儚甯︾殑鏅�鍙婏紝鎴愪汉褰辩墖鐨勫埗浣滃拰娑堣垂閮借繘鍏ヤ簡涓�涓�鍏ㄦ柊鐨勯樁娈点��
濡備粖锛屾棩鏈�鐨勬垚浜哄奖鐗囦骇涓氬凡缁忓舰鎴愪簡涓�鏉″畬鏁寸殑浜т笟閾撅紝鍖呮嫭鍒朵綔銆佸彂琛屻�侀攢鍞�鍜岃�傜湅绛夊�氫釜鐜�鑺傘�備笉鍚屼簬鏌愪簺鍥藉�讹紝鏃ユ湰鐨勬垚浜哄奖鐗囦笉浠呬粎鏄�鍗曠函鐨勮壊鎯呭唴瀹癸紝瀹冧滑甯稿父铻嶅悎浜嗗墽鎯呫�佽�掕壊鎵�婕旂瓑鍏冪礌锛屽惛寮曚簡澶ч噺瑙備紬銆�
### 浜屻�丆EAD-146鐨勫彂琛岃儗鏅�
CEAD绯诲垪鏄�涓�涓�骞垮彈娆㈣繋鐨勬垚浜哄奖鐗囩郴鍒楋紝閫氬父浠ュ叾楂樿川閲忕殑鍒朵綔鍜岀簿褰╃殑琛ㄦ紨闂诲悕銆傚敖绠�CEAD-146鐨勫叿浣撲俊鎭�鍙�鑳藉苟涓嶅箍涓轰汉鐭ワ紝浣嗗畠鏃犵枒鏄�鍦ㄨ繖涓�绯诲垪涓�鐨勪竴閮ㄩ噸瑕佷綔鍝侊紝鍙�鑳芥壙杞界潃鐙�鐗圭殑涓婚�樺拰椋庢牸銆�
鍦ㄦ垚浜哄奖鐗囦腑锛屾晠浜嬫儏鑺傚拰瑙掕壊璁惧畾寰�寰�鏄�鍚稿紩瑙備紬鐨勯噸瑕佸洜绱犮�侰EAD-146鍙�鑳藉洿缁曟煇绉嶇壒瀹氱殑鎯呮劅鎴栧够鎯冲睍寮�锛岄�氳繃鐢靛奖璇�瑷�浼犺揪鍑轰竴绉嶇壒鏈夌殑姘涘洿銆�
### 涓夈�佺ぞ浼氭枃鍖栬儗鏅�
鏃ユ湰绀句細瀵规垚浜哄奖鐗囩殑鎺ュ彈搴︾浉瀵硅緝楂樸�傚敖绠″湪鏃ユ湰鐨勬煇浜涘湴鍖猴紝鎴愪汉褰辩墖浠嶇劧瀛樺湪涓�瀹氱殑绀句細绂佸繉锛屼絾鏁翠綋鏉ョ湅锛岃繖涓�浜т笟宸茬粡铻嶅叆浜嗘棩甯哥敓娲汇�傚綍鍍忓簵銆佹垚浜哄奖闄㈢瓑鍦烘墍鐨勫瓨鍦�锛屼娇浜轰滑鍙�浠ユ柟渚垮湴鎺ヨЕ鍒拌繖绉嶅唴瀹广�傛瘡骞达紝鎴愪汉褰辩墖灞曡�堝拰棰佸�栧吀绀间篃鎴愪负涓氱晫鐨勭洓浜嬶紝鍚稿紩浜嗗ぇ閲忕殑瑙備紬鍜屽獟浣撳叧娉ㄣ��
姝ゅ�栵紝闅忕潃浜掕仈缃戠殑鏅�鍙婏紝鎴愪汉褰辩墖鐨勪紶鎾�鏂瑰紡鏃ョ泭澶氭牱鍖栥�備汉浠�鍙�浠ラ�氳繃鍚勭�嶅湪绾垮钩鍙拌�傜湅鍒版渶鏂扮殑鎴愪汉褰辩墖锛岃繖涓嶄粎鏀瑰彉浜嗚�備紬鐨勮�傜湅涔犳儻锛屼篃澧炲姞浜嗗競鍦虹殑绔炰簤銆�
### 鍥涖�佽�屼笟鎸戞垬涓庢満閬�
灏界�℃棩鏈�鎴愪汉褰辫�嗕骇涓氬彂灞曡繀閫燂紝浣嗕篃闈�涓寸潃涓�浜涙寫鎴樸�備竴鏂归潰锛屾硶寰嬫硶瑙勭殑涓嶆柇鍙樺寲浣垮緱琛屼笟鐨勮繍浣滃彉寰楀�嶆潅銆傚彟涓�鏂归潰锛屼簰鑱旂綉鐨勫叴璧疯櫧鐒跺甫鏉ヤ簡鏈洪亣锛屼絾涔熶娇寰楃洍鐗堝拰涓嶆�ｅ綋绔炰簤娉涙互锛岀粰姝ｇ増鍒朵綔閫犳垚浜嗗緢澶х殑鍐插嚮銆�
鐒惰�岋紝鍏堣繘鐨勫埗浣滄妧鏈�鍜屽�氭牱鍖栫殑鍐呭�逛粛鐒舵槸鏃ユ湰鎴愪汉褰辩墖鐨勪紭鍔裤�傞�氳繃涓嶆柇鍒涙柊鍜屼紭鍖栧埗浣滄祦绋嬶紝璁稿�氬埗浣滃叕鍙镐緷鐒惰兘澶熷湪甯傚満涓婂崰鏈変竴甯�涔嬪湴銆�
### 浜斻�佹�荤粨
CEAD-146浣滀负鏃ユ湰鎴愪汉褰辩墖绯诲垪涓�鐨勪竴閮ㄤ綔鍝侊紝铏界劧鍦ㄥ叿浣撶粏鑺備笂鍙�鑳戒笉涓哄ぇ浼楁墍鐔熸倝锛屼絾瀹冩墍浠ｈ〃鐨勮�屼笟鑳屾櫙鍜屾枃鍖栫幇璞″嵈鏄�鍊煎緱娣辨�濈殑銆傛棩鏈�鎴愪汉褰辫�嗕骇涓氱殑鍙戝睍涓嶄粎鍙嶆槧浜嗙ぞ浼氭枃鍖栫殑鍙樿縼锛屼篃浣撶幇浜嗕汉浠�瀵规�у拰鎯呮劅鐨勬帰绱�涓庤〃杈俱��
鏈�鏉ワ紝闅忕潃绀句細瑙傚康鐨勬敼鍙樺拰鎶�鏈�鐨勮繘姝ワ紝鎴愪汉褰辩墖浜т笟灏嗙户缁�婕斿彉骞堕�傚簲鏂扮殑甯傚満闇�姹傘�備汉浠�瀵规�у拰鎯呮劅鐨勭悊瑙ｄ篃灏嗚繘涓�姝ユ繁鍖栵紝淇冧娇杩欎竴琛屼笟鍦ㄥ悎瑙勪笌鍒涙柊涓�鏈濈潃鏇村姞鎴愮啛鐨勬柟鍚戣繄杩涖��